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      L871    AKSci Bulk Reagent
    7-MAC    , >95% (HPLC)
     
    Diphenylmethyl (6R,7S)-7-Amino-7-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    7-ACA-3-MTT-7-MO
    5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
    IDENTITY
    CAS Number:56610-72-1
    MDL Number:MFCD08704705
    MF:C24H24N6O4S2
    MW:524.62
    SPECIFICATIONS & PROPERTIES
    Min. Purity Spec:>95% (HPLC)
    Physical Form (at 20°C):Solid
    Melting Point:120-130°C
    Long-Term Storage:Store long-term at 2-8°C
    DOT/IATA TRANSPORT INFORMATION
    Not hazardous material

    BIOLOGICAL INFO
    Form:Free Base

    REVIEW
     7-MAC (7-methoxyaminocephalosporin) is a key intermediate in the preparation of number of cephalopsporin antibacterials, for example, cefotetan, cefmetazole, cefaclor, cefbuperazone and cefminox.

    REFERENCES
    [1]Koppel, Gary A. 7beta-Acylamido-7alpha-methoxycephalosporins Ger. Offen. (1975), DE 2451931 A1 19750507.
    [2] Iwamatsu, Katsuyoshi; Inouye, Shigeharu; Tsuruoka, Takashi; Mizutani, Kazuko; Omoto, Shoji; Ogino, Hiroko; Miyauchi, Keinosuke; Watanabe, Tadahiro; Niida, Taro Synthesis and biological activity of 7beta-[[(2-amino-2-carboxyethyl)thio]acetamido]-7alpha-methoxycephalosporin derivatives. Journal of Antibiotics (1983), 36(3), 229-41.
    [3] Ohi, Nobuhiro; Aoki, Bunya; Shinozaki, Teizo; Moro, Kanzi; Kuroki, Toshio; Noto, Takao; Nehashi, Toshiyuki; Matsumoto, Masahiko; Okazaki, Hiroshi; Matsunaga, Isao Semisynthetic β-lactam antibiotics. IV. Synthesis and antibacterial activity of new ureidocephalosporin and ureidocephamycin derivatives containing a catechol moiety or its acetate. Chemical & Pharmaceutical Bulletin (1987), 35(5), 1903-9.
    [4] Naito, Kenji; Morita, Tadashi; Kaneda, Soichi; A new process for the preparation of cefmetazole Jpn. Kokai Tokkyo Koho (1987), JP 62089689 A 19870424.

    GLOBALLY HARMONIZED SYSTEM (GHS)

    Pictograms

    Signal Word
    None

    Hazard Statements
    None

    Precautionary Statements
    Notavailable

    Current as of January 28, 2025


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    All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
    All batches backed with full quality assurance.
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    All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

    These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

    Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

    New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


    CATEGORIES
     APIs and Bioactives > Antibacterials


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