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  C716    
Torsemide
, 98% (HPLC)
 
N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
Demadex




IDENTITY
CAS Number:56211-40-6
MDL Number:MFCD00866166
MF:C16H20N4O3S
MW:348.42
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:160-165°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 18mg/mL; H2O: insoluble
Application(s):Sodium Potassium Chloride Symporter Inhibitor
Form:Free Base

REVIEW

 A pyridine-sulfonyl urea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension.

REFERENCES
[1]TORAFIC Investigators Group (2012). Effects of prolonged-release torasemide versus furosemide on myocardial fibrosis in hypertensive patients with chronic heart failure: a randomized, blinded-end point, active-controlled study. Clin Ther. 33(9):1204-1213.e3. PMID 21906812.
[2] Peddle GD, Singletary GE, Reynolds CA, Trafny DJ, Machen MC, Oyama MA (2012). Effect of torsemide and furosemide on clinical, laboratory, radiographic and quality of life variables in dogs with heart failure secondary to mitral valve disease. J Vet Cardiol. 14(1):253-9. PMID 22364690.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H319

Precautionary Statements
P264; P280; P305+P351+P338; P337+P313


Current as of November 8, 2024


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All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Diuretics


PubChem
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