REVIEW An advanced cephalosporin beta-lactam intermediate used in the preparation of antibiotcs eg. ceftaroline.
REFERENCES
[1]
Scartazzini, Riccardo; Bickel, Hans Modifications of antibiotics. 10. New beta-lactam antibiotics. Derivatives of 3-hydroxy-7-amino-3-cephem-4-carboxylic acid Helvetica Chimica Acta (1974), 57(7), 1919-34.
[2]
Woodward, Robert B.; Bickel, Hans 7beta-Amino-3-R1-thio-3-cephem-4-carboxylic acid derivatives Ger. Offen. (1976), DE 2537974 A1 19760311.
[3]
Balsamo, A.; Macchia, B.; Macchia, F.; Rossello, A.; Giani, R.; Pifferi, G.; Pinza, M.; Broccali, G. Synthesis and antibacterial activities of new (alpha-hydrazinobenzyl)cephalosporins Journal of Medicinal Chemistry (1983), 26(11), 1648-50.
[4]
Nishikawa, Junko; Tori, K. 3-Substituent effect and 3-methylene substituent effect on the structure-reactivity relationship of 7beta-(acylamino)-3-cephem-4-carboxylic acid derivatives studied by carbon-13 and IR spectroscopy Journal of Medicinal Chemistry (1984), 27(12), 1657-63.
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