REVIEW 5-Aminolevulinic acid hydrochloride is used as a photosensitizer for photodynamic detection and therapy for actinic keratosis. It is biosynthesized from succinyl-CoA and glycine and is the first compound in the porphyrin synthesis pathway. It elicits synthesis and accumulation of fluorescent porphyrins in epithelia and neoplastic tissues.
REFERENCES
[1]
Herdeis, Claus; Dimmerling, Anna A three-step synthesis of epsilon-aminolevulinic acid Archiv der Pharmazie (Weinheim, Germany) (1984), 317(4), 304-6.
[2]
Kawakami, Hiroshi; Ebata, Takashi; Matsushita, Hajime A new synthesis of 5-aminolevulinic acid Agricultural and Biological Chemistry (1991), 55(6), 1687-8.
[3]
Matsumura, Yoshihiro; Takeshima, Yo-ichiro; Okita, Hideki A convenient method for introducing oxo group into the beta-position of cyclic amines and its application to synthesis of epsilon-aminolevulinic acid Bulletin of the Chemical Society of Japan (1994), 67(1), 304-6.
[4]
Nokes B, Apel M, Jones C, Brown G, Lang JE.Aminolevulinic acid (ALA): photodynamic detection and potential therapeutic applications.J Surg Res. 2013 May;181(2):262-71.
All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
??
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
Add to Favorites 
Delete from Favorites 
