REVIEW A synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.
REFERENCES
[1]
McLean NJ, Ward DA, Hendrix DV, Vaughn RK (2012). Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. J Am Vet Med Assoc. 240(5):563-9. PMID 22332625.
[2]
Nien CJ, Flynn KJ, Chang M, Brown D, Jester JV (2011). Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%. J Cataract Refract Surg. 37(5):937-44. PMID 21406325.
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