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  J10166    AKSci Reference Standard
Flurbiprofen
, >98% (HPLC), powder
 
Cyclooxygenase inhibitor




IDENTITY
CAS Number:5104-49-4
MDL Number:MFCD00079303
MF:C15H13FO2
MW:244.26
EINECS:225-827-6
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:110-117°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:DMSO: 49mg/mL; H2O: <1mg/mL; EtOH: 49mg/mL; MeOH: 50mg/mL
Application(s):Cyclooxygenase Inhibitor
Form:Free Base

REVIEW

 A member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis.

REFERENCES
[1]Chow SF, Chen M, Shi L, Chow AH, Sun CC (2012). Simultaneously improving the mechanical properties, dissolution performance, and hygroscopicity of ibuprofen and flurbiprofen by cocrystallization with nicotinamide. Pharm Res. 29(7):1854-65. PMID 22359146.
[2] Matzneller P, Burian A, Martin W, Annoni O, Lauro V, Tacchi R, Brunner M, Zeitlinger M (2012). A randomised, two-period, cross-over, open-label study to evaluate the pharmacokinetic profiles of single doses of two different flurbiprofen 8.75-mg lozenges in healthy volunteers. Pharmacology. 89(3-4):188-91. PMID 22433300.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301

Precautionary Statements
P264; P270; P301+P310; P321; P330; P405; P501


Current as of December 23, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
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WARNING: Attention California residents: This product can expose you to chemicals including Flurbiprofen, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.




CATEGORIES

 APIs and Bioactives > NSAIDs


PubChem
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