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  P888    AKSci Bulk Reagent
Acipimox
, 98% (HPLC)
 
2-Carboxy-5-methylpyrazine 4-oxide
5-Methylpyrazinecarboxylic acid 4-oxide
5-methylpyrazine-2-carboxylic acid 4-oxide
more..




IDENTITY
CAS Number:51037-30-0
MDL Number:MFCD00865757
MF:C6H6N2O3
MW:154.12
EINECS:256-928-3
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:177-180°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 31mg/mL
Application(s):Hypolipidemic Agent
Form:Free Base

REVIEW

 Acipimox, an anti-lipoytic drug and vasodilator, is used in studies involving lipolysis. Acipimox may be used in various metabolic studies involving insulin and ghrelin.

REFERENCES
[1]Lim EL, Hollingsworth KG, Smith FE, Thelwall PE, Taylor R (2011). Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates. Clin Sci (Lond). 121(4):169-77. PMID 21388348.
[2] Montecucco F, Bertolotto M, Vuilleumier N, Franciosi U, Puddu A, Minetti S, Delrio A, Quercioli A, Bergamini E, Ottonello L, Pende A, Lenglet S, Pelli G, Mach F, Dallegri F, Viviani GL (2011). Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome. Am J Physiol Endocrinol Metab. 300(4):E681-90. PMID 21266669.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H319

Precautionary Statements
P264; P280; P305+P351+P338; P337+P313


Current as of January 9, 2025


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Hypercholesterolemia


PubChem
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