REVIEW Norfenefrine (brand names Coritat, Energona, Hypolind, and Novadral), also known as m-octopamine (or 3-octopamine) and 3, alpha-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico, where it is used in the treatment of hypertension. Along with its structural isomer p-octopamine and the tyramines, norfenefrine is a naturally occurring, endogenous trace amine and plays a role as a minor neurotransmitter in the brain.
REFERENCES
[1]
Gebler, Herbert Novadral [drug report]. der Praktischen Pharmazie (1979), 8(7), 218-19.
[2]
Danielson TJ, Boulton AA, Robertson HA. m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs. J Neurochem. 1977 Dec;29(6):1131-5.
[3]
Fregly, Melvin J.; Kelleher, D. L.; Williams, C. M. Adrenergic activity of ortho-, meta-, and para-octopamine. Pharmacology (1979), 18(4), 180-7.
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