REVIEW Dodine is a guanidine derivative and acts predominantly as a protective fungicide, but also has a small degree of curative action. Its greatest use is in apples, pears and pecans for the control of V. inaequalis (black spot or scab) and it is also used against a limited range of other diseases. These include leaf spot diseases of cherries, olives, blackcurrants, celery, and other crops; and foliar diseases of strawberries. Also used on other fruit, vegetable, nut, and ornamental crops, and on shade trees. Dodine causes in cell death and leakage of potassiumins, UV-absorbing materials, and ribose-containing molecule; dodine causes gross and extensive damage to the cytoplasmic membrane, which is probably implicated in the death of cells.
REFERENCES
[1]
Gagliardi, George N Alkylguanidine salts, US 3004065 19611010.
[2]
Byrde, R. J. W.; Clifford, D. R.; Woodcock, D Fungicidal activity and chemical constitution. XI. The activity of n alkyl guanidine acetates Annals of Applied Biology (1962), 50, 291-8.
[3]
Cabral JP.Damage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271. Antimicrob Agents Chemother. 1991 Feb;35(2):341-4.
[4]
Cabral JP.Mode of antibacterial action of dodine (dodecylguanidine monoacetate) in Pseudomonas syringae. Can J Microbiol. 1992 Feb;38(2):115-23.
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