REVIEW Methoxydienone is a steroidal compounds used as an advanced intermediate for the synthesis of (-)-norgestral, mestranol, evonorgestrel and a range of biologically active steroids.
REFERENCES
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Wong, Fung Fuh; Chuang, Shih Hsien; Yang, Sheng-chuan; Lin, Yu-Hsiang; Tseng, Wen-Che; Lin, Shao-Kai; Huang, Jiann-Jyh. One-pot ethynylation and catalytic desilylation in synthesis of mestranol and levonorgestrel. Tetrahedron. (2010) 66(23): 4068-4072.
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Gao, Hongwu; Su, Xiangdong; Huang, Lei; Li, Zhensu. In improved synthesis of 13?-ethyl-11-methylenegon-4-ene-3,17-dione. Synthetic Communications. (1997) 27(11): 1981-1987.
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Baier, Helmut; Duerner, Gerd; Quinkert, Gerhard. Total synthesis of (-)-norgestrel. Helvetica Chimica Acta. (1985) 68(4): 1054-68.
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Liu, Li-Gong; Zhang, Tong; Li, Zhen-Su Silica gel promoted selective hydrolysis of 3-methoxy-2,5(10)-diene steroids Synthetic Communications (1996), 26(16), 2999-3006.
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