REVIEW Calcium dobesilate monohydrate is a synthetic product and a vasoprotective. It reduces blood hyper viscosity thus restoring normal flow and prevents platelet hyper-aggregation. This is the calcium salt of dobesilic acid. Calcium dobesilate monohydrate reduces capillary hyper-permeability, reduces oedema by stimulating lymph and reduces vessel fragility and thus strengthening them.
REFERENCES
[1]
Angulo J, Peiró C, Romacho T, Fernández A, Cuevas B, González-Corrochano R, Giménez-Gallego G, de Tejada IS, Sánchez-Ferrer CF, Cuevas P (2011). Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol. 667(1-3):153-9. PMID 21703259.
[2]
Miles JE, Wenck A, Fricker C, Svalastoga EL (2011). Modulation of the intramedullary pressure responses by calcium dobesilate in a rabbit knee model of osteoarthritis. Acta Orthop. 82(5):622-7. PMID 21895501.
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