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  E326    AKSci Bulk Reagent
3-(4-Hydroxy-3,5-diiodo)-benzoyl-2-butyl benzofuran, 98% (HPLC)
 
(2-Butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
(2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)ketone
IDENTITY
CAS Number:1951-26-4
MDL Number:MFCD02675787
MF:C19H16I2O3
MW:546.14
EINECS:217-773-7
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:144-148°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Soluble in methanol, and DMSO
Application(s):An analog of Amiodarone

REVIEW
 3-(4-Hydroxy-3,5-diiodo)-benzoyl-2-butyl benzofuran is an analog of the anti-arrhythmic compound Amiodarone HCl (Cat # F462). It results from O-dealkylation of the parent compound. Analogs of Amiodarone including this one were demonstrated to competitively inhibit 5'-T4 (thyroxine) deiodination.

REFERENCES
[1]Bigler, Laurent; European Journal of Medicinal Chemistry 2007, V42(6), P861-867
[2] Snead, Aaron N.; Bioorganic & Medicinal Chemistry Letters 2008, V18(22), P5920-5922
[3] Ha, H.R., et al. 2000. Eur. J. Clin. Pharmacol. 55: 807-814. PMID: 10805058

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
F462Amiodarone HCl
E3263-(4-Hydroxy-3,5-diiodo)-benzoyl-2-butyl benzofuran

Current as of November 8, 2024


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All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Arrhythmia


PubChem
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