REVIEW (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone is a key advanced intermediate used in the preparation of ezetimibe.
REFERENCES
[1]
Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-Hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones and intermediates for use as hypocholesterolemics PCT Int. Appl. (2000), WO 2000034240 A1 20000615.
[2]
Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones U.S. (2001), US 6207822 B1 20010327.
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Thiruvengadam, Tiruvettipuram K.; Chiu, John S.; Fu, Xiaoyong; McAllister, Timothy L. Process for the synthesis of azetidinones U.S. Pat. Appl. Publ. (2006), US 20060135755 A1 20060622.
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Barden, Timothy C.; Lee, Peter; Martinez, Eduardo J.; Schairer, Wayne C.; Talley, John J. Processes for production of phenolic 4-biphenylylazetidin-2-ones PCT Int. Appl. (2006), WO 2006122216 A2 20061116.
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