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  J93186    
Pizotifen
, 98%
 



IDENTITY
CAS Number:15574-96-6
MDL Number:MFCD00864192
MF:C19H21NS
MW:295.44
EINECS:239-632-9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:147-152°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >=8mg/mL
Application(s):Serotonin Antagonist
Form:Free Base

REVIEW

 Pizotifen is a a benzocycloheptene-based druge and a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some sedating antihistamine activity. It is used as a preventative to reduce the frequency of recurrent migraine headaches.

REFERENCES
[1]Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W (2011). Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 7(12):e1002310. PMID 22194678.
[2] Serna-Jim?nez CE, del Rio Sancho S, Calatayud-Pascual MA, Balaguer-Fern?ndez C, Femen?a-Font A, L?pez-Castellano A, Merino V (2012). HPLC-UV analytical method for determination of pizotifen after in vitro transdermal diffusion studies. Biomed Chromatogr. 26(6):769-74. PMID 22002332.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H361

Precautionary Statements
P201; P202; P264; P270; P281; P301+P312; P308+P313; P330; P405; P501


Current as of November 20, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

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