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  N722    AKSci Bulk Reagent
7-Phenylacetamido-3-chloromethyl-3-cephem-4-carboxylic acid-p-methoxybenzyl ester
, 98% (N)
 
4-Methoxybenzyl 3-Chloromethyl-7-(2-phenylacetamido)-3-cephem-4-carboxylate




IDENTITY
CAS Number:104146-10-3
MDL Number:MFCD00191253
MF:C24H23ClN2O5S
MW:486.97
BRN:4894110
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (N)
Physical Form (at 20°C):Solid
Melting Point:163-169°C
Optical Rotation:-44° (c=1%, CDCl3)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 An advanced cephalosporin beta-lactam intermediate used in the preparation of antibiotics.

REFERENCES
[1]Yamauchi, Hiroshi; Sugiyama, Isao; Saito, Isao; Nomoto, Seiichiro; Kamiya, Takashi; Machida, Yoshimasa; Negi, Shigeto Cephem derivatives Eur. Pat. Appl. (1986), EP 188255 A2 19860723.
[2] Nishide, Kiyoharu; Yamamura, Mariko; Kobori, Takeo; Tunemoto, Daiei; Kondo, Kiyosi; Sato, Kiyoshi A synthesis of new 3-dialkoxyphosphinylmethyl and 3-dihydroxyphosphinylmethyl cephalosporins Chemical & Pharmaceutical Bulletin (1988), 36(7), 2354-61.
[3] Farina, Vittorio; Baker, Stephen R.; Benigni, Daniel A.; Hauck, Sheila I.; Sapino, Chester, Jr. Palladium catalysis in cephalosporin chemistry: general methodology for the synthesis of cephem side chains Journal of Organic Chemistry (1990), 55(23), 5833-47.
[4] Sakagami, Kenji; Atsumi, Kunio; Tamura, Atsushi; Yoshida, Takashi; Nishihata, Ken; Fukatsu, Shunzo Synthesis and oral activity of ME 1207, a new orally active cephalosporin Journal of Antibiotics (1990), 43(8), 1047-50.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable


Current as of November 7, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Cephalosporins


PubChem
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