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Postion:Product Catalog >ZLN005
ZLN005
  • ZLN005

ZLN005 NEW

Price $31 $51 $92
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: ZLN005 CAS No.: 49671-76-3
Purity: 99.8% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱ZLN005
描述ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.
體外活性ZLN005 (15 mg/kg, p.o.) exhibits anti-hyperglycemic and anti-hyperlipidemic effects, and enhances insulin sensitivity in db/db mice without effecting lean mice.
體內(nèi)活性In L6 myotubes, ZLN005 enhances glucose uptake and fatty acid oxidation by activating AMP-activated protein kinase (AMPK), and it elevates the expression of PGC-1α genes and downstream genes without significant toxicity. However, the same effects are not observed in primary rat hepatocytes, indicating cell-specific actions.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度Ethanol : 2 mg/mL (7.98 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 60 mg/mL (239.67 mM)
關(guān)鍵字inhibit | ZLN 005 | Inhibitor | PPARγ coactivator-1α | ZLN005 | PGC-1α | ZLN-005 | Autophagy
相關(guān)產(chǎn)品Stavudine | Xylitol | Myricetin | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib
相關(guān)庫糖代謝化合物庫 | 表型篩選靶點鑒定庫 | 經(jīng)典已知活性庫 | 自噬庫 | NO PAINS 化合物庫 | 脂代謝化合物庫 | 代謝化合物庫 | 已知活性化合物庫 | 抗代謝疾病化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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