ZLN005 NEW
Price | $31 | $51 | $92 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: ZLN005 | CAS No.: 49671-76-3 |
Purity: 99.8% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | ZLN005 |
描述 | ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α. |
體外活性 | ZLN005 (15 mg/kg, p.o.) exhibits anti-hyperglycemic and anti-hyperlipidemic effects, and enhances insulin sensitivity in db/db mice without effecting lean mice. |
體內(nèi)活性 | In L6 myotubes, ZLN005 enhances glucose uptake and fatty acid oxidation by activating AMP-activated protein kinase (AMPK), and it elevates the expression of PGC-1α genes and downstream genes without significant toxicity. However, the same effects are not observed in primary rat hepatocytes, indicating cell-specific actions. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | Ethanol : 2 mg/mL (7.98 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 60 mg/mL (239.67 mM) |
關(guān)鍵字 | inhibit | ZLN 005 | Inhibitor | PPARγ coactivator-1α | ZLN005 | PGC-1α | ZLN-005 | Autophagy |
相關(guān)產(chǎn)品 | Stavudine | Xylitol | Myricetin | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib |
相關(guān)庫 | 糖代謝化合物庫 | 表型篩選靶點鑒定庫 | 經(jīng)典已知活性庫 | 自噬庫 | NO PAINS 化合物庫 | 脂代謝化合物庫 | 代謝化合物庫 | 已知活性化合物庫 | 抗代謝疾病化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$1.00/1ASSAYS |
VIP7Y
|
Career Henan Chemical Co
|
2019-09-04 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY