Zinc Protoporphyrin NEW
Price | $49 | Get Latest Price | Get Latest Price |
Package | 5mg | 10mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: Zinc Protoporphyrin | CAS No.: 15442-64-5 |
Purity: 99.27% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | Zinc Protoporphyrin |
描述 | Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active, competitive inhibitor of heme oxygenase-1 (HO-1) that markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 and exhibits anti-cancer activity. |
體外活性 | Zinc Protoporphyrin (Zn(II)-protoporphyrin IX; 5 μM; 72 hours) increased the proportion of late apoptosis and necrotic cells from 10.9% in the control group to 30.4% after 72 hours [3]. Zinc Protoporphyrin (1.25-40 μM; 48 or 72 hours) exerts cystostatic/cytotoxic effects against tumor cells[3]. Zinc Protoporphyrin (2.5, 5 μM; 48 or 72 hours) results in dose- and time-dependent reduction of cells in G1 phase of the cell cycle[3]. Zinc Protoporphyrin (1.25-40 μM; 48 hours) leads to accumulation of cleaved (active) caspase-3[3]. |
體內活性 | Zinc Protoporphyrin exhibits dose-dependent antitumor effects manifested by the retardation of tumor growth[3]. |
存儲條件 | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (79.87 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
關鍵字 | Zinc Protoporphyrin | screening | Zinc Protoporphyrin9 | heme | iron | inhibit | Phloroglucinol | deficiency,anti-cancer | Reactive Oxygen Species | Inhibitor | marker | Apoptosis | H2O2 | Endogenous Metabolite | HO-1 | oxygenase-1 | Zinc Protoporphyrin 9 |
相關產品 | Sucrose | Stavudine | Daidzein | Guanidine hydrochloride | Fumaric acid | Tributyrin | Ferulic Acid | Glycerol | Thymidine | Naringin |
相關庫 | NF-κB 通路分子庫 | 經典已知活性庫 | 抗卵巢癌化合物庫 | 抑制劑庫 | 線粒體靶向庫 | 口服活性化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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