Zebularine NEW

Price	$38	$58	$127
Package	5mg	10mg	25mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-07

Product Details

Product Name: Zebularine	CAS No.: 3690-10-6
Purity: 99.84%	Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱	Zebularine
描述	Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2 μM, in a cell-free assay).
細(xì)胞實(shí)驗(yàn)	For methylation analysis, 10T1/2 cells and T24 cells are treated with the various concentrations of zebularine. For 10T1/2 cells, the medium is changed 24 hours after the initial drug treatment, whereas for T24 cells, the medium is changed 24 hours or 48 hours after the initial drug treatment. DNA and RNA are harvested from 10T1/2 cells 72 hours after initial drug treatment and from T24 cells 96 hours after initial drug treatment. The methylation status of the indicated DNA regions is measured in two separate and independent experiments, both of which are done in duplicate[2].
存儲(chǔ)條件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度	DMSO : 60 mg/mL (262.93 mM) H2O : 22.8 mg/mL (100 mM)
關(guān)鍵字	DNMTs \| Inhibitor \| DNA MTases \| NSC-309132 \| Zebularine \| Autophagy \| DNA Methyltransferase \| NSC 309132 \| inhibit
相關(guān)產(chǎn)品	Stavudine \| Xylitol \| Myricetin \| Sodium 4-phenylbutyrate \| Hydroxychloroquine \| Guanidine hydrochloride \| Taurine \| Curcumin \| Oxyresveratrol \| Paeonol \| Naringin \| Gefitinib
相關(guān)庫	高選擇性抑制劑庫 \| 甲基化化合物庫 \| 細(xì)胞重編程化合物庫 \| 經(jīng)典已知活性庫 \| 表觀遺傳庫 \| 抗病毒庫 \| 抑制劑庫 \| 抗衰老化合物庫 \| 已知活性化合物庫 \| 共價(jià)抑制劑庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.