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Postion:Product Catalog >zapnometinib
zapnometinib
  • zapnometinib

zapnometinib NEW

Price $40 $60 $73
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: zapnometinib CAS No.: 303175-44-2
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Namezapnometinib
DescriptionZapnometinib (ATR-002) is a MEK inhibitor.
In vitroZapnometinib inhibits MEK, with IC50s of 30.96 nM, 357 nM, and 15 nM in cell free kinase assay, A549, MDCK cells and human PBMCs[1].Zapnometinib reduces the viral titers of the IV H1N1pdm09, H3N2[1].
In vivoZapnometinib exhibits AUC values of 860.02 and 1953.68 μg?h/mL in mice by i.v. or oral route, respectively[1].Zapnometinib reduces the lung virus titers and enhances survival of mice after lethal H1N1pdm09 infection[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (146.50 mM)
Keywordsantiviral | virus | MAPKK | Influenza Virus | Bacterial | PD-0184264 | CI-1040 | ATR 002 | Inhibitor | Mitogen-activated protein kinase kinase | antibacterial | zapnometinib | inhibit | ATR002 | influenza | PD 0184264 | MAP2K | MEK
Inhibitors RelatedNeomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Curcumin | Dimethyl sulfoxide | Crystal Violet
Related Compound LibrariesReprogramming Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Anti-Viral Compound Library | Inhibitor Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | MAPK Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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