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Postion:Product Catalog >Zamicastat
Zamicastat
  • Zamicastat

Zamicastat NEW

Price $88 $215 $325
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Zamicastat CAS No.: 1080028-80-3
Purity: 99.58% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameZamicastat
DescriptionZamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 μM and 17.0 μM, respectively.
In vivoIn the Dahl SS rat, Zamicastat (10, 30 and 100 mg/kg/day; oral bolus, 7 days) is tested acutely against salt-induced hypertension. Zamicastat produces a dose-dependent decrease in blood pressure[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 150 mg/mL (373.63 mM), Sonication is recommended.
KeywordsABCB1 | Dopamine β-monooxygenase | Inhibitor | Cluster of differentiation 243 | ABCG2 | inhibit | P-glycoprotein | Multidrug resistance protein 1 | BCRP | MDR1 | CD243 | Breast cancer resistance protein | P-gp | Pgp | Zamicastat | Dopamine β-hydroxylase | Dopamine beta-hydroxylase | Dopamine beta-monooxygenase
Inhibitors RelatedAtazanavir | Verapamil hydrochloride | Glibenclamide | Encequidar mesylate | Casein | Ketoconazole | Polyoxyethylene stearate | Elacridar | P-gp inhibitor 1 | Fenclonine | Cinchonine | Atazanavir sulfate
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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