Zalcitabine NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-12-09 |
Product Details
| Product Name: Zalcitabine | CAS No.: 7481-89-2 |
| EC-No.: 620-762-3 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/12/09 |
| CAS: | 7481-89-2 |
| MF: | C9H13N3O3 |
| MW: | 211.22 |
| EINECS: | 620-762-3 |
| Product Categories: | Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Pharmaceutical Raw Materials;Miscellaneous Biochemicals;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Other APIs;Inhibitors |
| Mol File: | 7481-89-2.mol |
 | |
| Zalcitabine Chemical Properties |
| Melting point | 217-218 °C(lit.) |
| alpha | D25 +81° (c = 0.635 in water) |
| Boiling point | 350.9°C (rough estimate) |
| density | 1.2605 (rough estimate) |
| refractive index | 78 ° (C=0.5, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | powder |
| pka | 14.44±0.10(Predicted) |
| color | colorless |
| Water Solubility | 5-10 g/100 mL at 19 oC |
| Merck | 14,10109 |
| BRN | 654956 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | WREGKURFCTUGRC-POYBYMJQSA-N |
| CAS DataBase Reference | 7481-89-2(CAS DataBase Reference) |
| IARC | 2B (Vol. 76) 2000 |
| EPA Substance Registry System | Cytidine, 2',3'-dideoxy- (7481-89-2) |
| Zalcitabine Usage And Synthesis |
| Description | Zalcitabine is an orally active dideoxynucleoside andog for combination use with zidovudine in advanced HIV infection and also as monotherapy for AIDS patients who cannot tolerate or have not responded to zidovudine. It has a similar mechanism of action (inhibition of reverse transcriptase) to didanosine. Like didanosine, its side effect profile includes peripheral neuropathy. Unlike zidovudine, zalcitabine does not cause bone marrow suppression. |
| Description | Zalcitabine is an analog of pyrimidine derived from deoxycytidine with the replacement of the hydroxyl group in position 3’ with a hydrogen. In cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. Zalcitabine was the third antiretroviral approved by the FDA for treatment of HIV infection and AIDS. |
| Chemical Properties | White to Off-White Cyrstalline Powder |
| Originator | National Cancer Institute (NIH) (U.S.A.) |
| Uses | ammonia detoxicant, diagnostic aid |
| Uses | A pyrimidine nucleoside analogue with antiviral activity. |
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
13288715578
sales@hbmojin.com