YTX-465 NEW
| Price | $176 | $373 | $590 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: YTX-465 | CAS No.: 2225824-53-1 |
| Purity: 99.41% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | YTX-465 |
| Description | YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM). |
| In vitro | YTX-465 rescued growth to a similar magnitude but was >100-fold more potent than YTX-528(EC50 = 0.013 μM). Kinetic growth studies demonstrated that the most effective concentration of YTX-465 (0.050 μM) restored growth rates to that of approximately 40% of the wild-type strain treated with the same concentration of YTX-465[1]. In wild-type yeast, YTX-465 strongly reduced fatty desaturation in a concentration-dependent manner, with a 50% reduction in desaturation at 0.03 μM YTX-465[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (109.05 mM) |
| Keywords | α-synuclein | fatty desaturation | Stearoyl-CoA Desaturase (SCD) | YTX 465 | Inhibitor | Parkinson’s disease | YTX465 | inhibit | synucleinopathies | YTX-465 |
| Inhibitors Related | SSI-4 | Elemicin | PluriSIn 1 | MK-8245 | SLC13A5-IN-1 | CAY10566 | MF-438 | A939572 | XEN723 | SCD1 inhibitor-4 | GSK1940029 | CVT-12012 |
| Related Compound Libraries | Bioactive Compound Library | Anti-Obesity Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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