WITHAFERIN A NEW
| Price | $77 | $279 | $413 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: WITHAFERIN A | CAS No.: 5119-48-2 |
| Purity: 99.83% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | WITHAFERIN A |
| 描述 | WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer. |
| 細胞實驗 | L929sA cells were co-treated with WITHAFERIN A and DTT for 1 h, and then TNF-induced NFκB activation was examined. |
| 動物實驗 | Mice are injected subcutaneously with zymosan in the footpad, and swelling is determined at several time points after the injection. Pretreatment with WITHAFERIN A(intraperitoneal) was performed to evaluate anti-inflammatory effects, whereas DEX (intraperitoneal) was chosen as a positive control. the mean of the differences between the zymosan-treated and untreated footpad for all the three groups. Both DEX. |
| 體外活性 | WITHAFERIN A,potently inhibits NFkappaB activation by preventing the tumor necrosis factor-induced activation of IkappaB kinase beta via a thioalkylation-sensitive redox mechanism. |
| 體內活性 | WITHAFERIN A Displays Anti-inflammatory Properties in Vivo—Because NFκB is a critical player in the inflammatory signaling pathway and because WITHAFERIN A inhibits NFκB activation. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 27.5 mg/mL (58.44 mM) |
| 關鍵字 | NF-κB | Nuclear factor-κB | WITHAFERIN A | Inhibitor | Ferroptosis | Nuclear factor-kappaB | inhibit |
| 相關產品 | TBHQ | α-Vitamin E | Sorafenib | Diethylmaleate | Curcumin | Glucosamine | Lidocaine hydrochloride | Artemisinin | L-Cystine | L-Glutamic acid monosodium salt | Indole-3-carbinol | Diallyl disulfide |
| 相關庫 | 抗癌天然產物庫 | 經(jīng)典已知活性庫 | 植物來源化合物庫 | 中藥抗炎分子庫 | 天然產物庫 | 抑制劑庫 | 高通量篩選天然產物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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