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Postion:Product Catalog >VU6005649
VU6005649
  • VU6005649

VU6005649 NEW

Price $34 $53 $107
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: VU6005649 CAS No.: 2137047-43-7
Purity: 99.79% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱VU6005649
描述VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
體外活性VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor(EC50s of 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively). VU6005649 displays a terminal Kp of 2.43 with total brain levels ~9× above the mGlu7 positive allosteric modulator (PAM) in vitro EC50.
體內(nèi)活性In wild-type mice VU6005649 shows modest but significant pro-cognitive effects on associative learning and the first example of efficacy of an mGlu7/8 positive allosteric modulator (PAM) in this model.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 60 mg/ml (167.94 mM), Sonication is recommended.
關(guān)鍵字VU-6005649 | VU6005649 | Inhibitor | inhibit | VU 6005649 | mGluR | Metabotropic glutamate receptors
相關(guān)產(chǎn)品IDRA-21 | Topiramate | Decanoic Acid | Urethane | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine | Memantine hydrochloride
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$34.00/5mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-11
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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