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Postion:Product Catalog >API>Antineoplastic agents>Natural sources of antineoplastic>Vincristine Sulfate
Vincristine Sulfate
  • Vincristine Sulfate
  • Vincristine Sulfate
  • Vincristine Sulfate
  • Vincristine Sulfate
  • Vincristine Sulfate

Vincristine Sulfate NEW

Price Get Latest Price
Package 25kg
Min. Order: 1kg
Supply Ability: 2000ton
Update Time: 2024-04-12

Product Details

Product Name: Vincristine Sulfate CAS No.: 2068-78-2
EC-No.: 218-190-0 Min. Order: 1kg
Purity: 99% Supply Ability: 2000ton
Release date: 2024/04/12
Appearance: White Powder

Vincristine, the trade name "Vicostine", "ankopin" (Oncovin), also known as vincristine, neovincristine, medically referred to as VCR, is a kind of alkaloid extracted from the spring flower plant Vinca in the phlox family. It is a mitotic inhibitor and is widely used in chemotherapy to treat a variety of cancers, including acute lymphoblastic leukemia, acute myeloid leukemia, Hodgkin's lymphoma, neuroblastoma, and small cell lung cancer. Vincristine sulfate is its sulfate form.

 

Pharmacological action

VCR is a cell cycle-specific anti-tumor drug of Vinca alkaloids in the oleandaceae family. The anti-tumor target is microtubule, which mainly inhibits the polymerization of microtubulin and affects the formation of spindle microtubules, thus stopping mitosis in the middle stage.


Clinical application

Like other vinca alkaloids, VCR has been shown to be effective in the treatment of many lymphatic malignancies, including aggressive non-Hodgkin lymphoma and acute lymphoblastic leukemia. It is mainly used in the treatment of acute leukemia, malignant lymphoma, neuroblastoma, chronic lymphocytic leukemia and other diseases.


Application:

A sulfate of a natural alkaloid, isolated from the plant vincristine and having anti-mitotic and anti-tumor activities. Vincristine irreversibly binds to microtubules and spindle proteins during the S phase of the cell cycle, interfering with mitotic spindle formation and thereby inhibiting tumor cells in the middle phase. Depolymerize microtubules and may interfere with the metabolism of amino acids, cyclic adenylate and glutathione.

Storage Condition

Keep in a cool and dry place

Transportation

By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS)

Delivery Time

7-28 days

Payment

T/T, Western Union or Bitcoin

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Company Profile Introduction

Xi'an Haibo Biotechnology Co.,Ltd. is specialized in the study, production and sale of natural plant extract products,which are used in pharmaceuticaldietary supplement, food and cosmetic industries. Our company is located in Xian National High-tech Industrial Development Zone. Xian Haibo Biotech Co.,Ltd. has a number of departments including R&D, production, quality inspection, and market. The company's R&D center has a technical team specializing in research and developmentas well as advanced detection systems such as high-performance liquid chromatography, gas chromatography,and magnetic drive autoclave, experimental, pilot plant,and a number of scientific research institutions have established a good technical support relationship,with strong technical force. The company's production workshop has several plant extraction production lines, as well as advanced production equipment such as dynamic countercurrent extraction,column separatio

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  • Since: 2020-08-05
  • Address: 804, Unit 2, Building 4, i City, No. 11, South Tangyan Road, High-tech Zone, Xi 'an, Shaanxi
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