USP7-IN-12 NEW
Price | Get Latest Price | |
Package | 5mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: USP7-IN-12 | CAS No.: 2763698-01-5 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | USP7-IN-12 |
Description | USP7-IN-12 (compound 1) is a potent, orally active Usp7 inhibitor with an IC50 of 3.67 nM, demonstrating antiproliferative activity [1]. |
In vitro | USP7-IN-12 (compound 1), following a 72-hour incubation period, exhibited antiproliferative activity, with an IC50 value of 69.5 nM against RS4;11 [1]. |
In vivo | USP7-IN-12 (5 mg/kg; oral) exhibited favorable pharmacokinetic properties in male SD rats: a half-life (T1/2) of 3.68 hours, time to maximum concentration (Tmax) of 3.33 hours, peak concentration (Cmax) of 330 ng/mL, and area under the curve from time zero to infinity (AUC0-inf) of 2014 hr*ng/mL [1]. |
Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Since: 2011-01-07
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