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Postion:Product Catalog >XL 999
XL 999
  • XL 999

XL 999 NEW

Price $35 $56 $98
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: XL 999 CAS No.: 705946-27-6
Purity: 99.55% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameXL 999
DescriptionTyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor that acts on KDR, Flt-1, FGFR1, and PDGFRα with IC50 values of 4 nM, 20 nM, 4 nM, and 2 nM, respectively.
In vivoTyrosine kinase-IN-1 demonstrates a reasonable pharmacokinetic profile [AUC(0–∞)=1.9, t1/2=4.6 h] and possesses favorable oral bioavailability (F=63%) in rats.
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 62.5 mg/mL (160.47 mM)
KeywordsVEGFR | Vascular endothelial growth factor receptor | Tyrosine kinase-IN-1 | Tyrosine kinaseIN1 | Tyrosine kinase IN 1 | Platelet-derived growth factor receptor | PDGFR | Inhibitor | inhibit | Fibroblast growth factor receptor | FGFR
Inhibitors RelatedRibociclib | Gilteritinib | Amlexanox | Nintedanib | Regorafenib monohydrate | Sorafenib | Ferulic Acid | Regorafenib | Formononetin | Imatinib | Pazopanib | Axitinib
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Osteogenesis Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Inhibitor Library | Anti-Fibrosis Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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