Product Details
Product Name:
TV 3279 |
CAS No.:
209394-29-6 |
Purity:
97% |
Supply Ability:
10g |
Release date:
2024/11/16 |
Product Introduction
Bioactivity
名稱 | TV 3279 |
描述 | TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apoptotic enzyme glyceraldehyde phosphate dehydrogenase in PC-12 and neuroblastoma cells. |
體內(nèi)活性 | Chronic TV3279 (26 mg kg-1 for 21 days; rats) similarly inhibited ~50% of striatal ChE activity but did not affect MAO activity or amine levels. Accordingly, chronic TV3279 abolished the ability of TCP to initiate L-dopa-induced hyperactivity. In contrast, chronic as well as acute treatments with TV3279 reduced spontaneous motor activity.[2] |
存儲條件 | Shipping with blue ice. |
溶解度 | DMSO : 2.73 mg/mL (10.01 mM)
|
關(guān)鍵字 | TV3279 | TV-3279 | TV 3279 |
相關(guān)產(chǎn)品 | (S)-(+)-Ibuprofen | Darovasertib | Ellagic acid | α-Vitamin E | Ro-3306 | Staurosporine | Navitoclax | Lisaftoclax | N-Desmethyltamoxifen hydrochloride | Venetoclax | Mitoxantrone dihydrochloride | R59949 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 神經(jīng)保護化合物庫 | 抑制劑庫 | 線粒體靶向庫 | 抗衰老化合物庫 | 已知活性化合物庫 | TGF-β/Smad靶點化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$0.00/1kg |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-09-30 |