TS-011 NEW
| Price | $108 | $198 | $311 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: TS-011 | CAS No.: 339071-18-0 |
| Purity: 99.48% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | TS-011 |
| Description | N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide (TS-011) is a selective 20-Hydroxyeicosatetraenoic acid synthesis inhibitor. |
| In vivo | Administered at a dose of 0.3 mg/kg, TS-011 effectively inhibits the decrease in blood flow velocities observed at 1 and 7 hours post-reperfusion, as evidenced by significant statistical values (P<0.001), and prevents the acceleration of blood flow velocity at 24 hours after reperfusion (P<0.01). Additionally, this dosage of TS-011 substantially reduces the volume of infarcts by nearly 40% (P<0.05) and maintains microvascular perfusion areas, which are otherwise diminished in mice treated with a standard vehicle [1]. Furthermore, in a study involving 9 dogs experiencing delayed vasospasm, an acute intervention with TS-011 (1 mg/kg IV) markedly enlarged the basilar artery's diameter by 39%, illustrating a significant impact on vascular health [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 240 mg/mL (938.60 mM), Sonication is recommended. |
| Keywords | Inhibitor | N (3 Chloro 4 morpholinophenyl) N' hydroxyformimidamide | N(3Chloro4morpholinophenyl)N'hydroxyformimidamide | TS 011 | inhibit | TS011 |
| Related Compound Libraries | Bioactive Compound Library | ReFRAME Related Library | Inhibitor Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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