Tris(2,4-di-tert-butylphenyl)phosphate NEW
| Price | $30 | $42 | $61 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Tris(2,4-di-tert-butylphenyl)phosphate | CAS No.: 95906-11-9 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Tris(2,4-di-tert-butylphenyl)phosphate |
| Description | Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) isolated from Vitex negundoL inhibits secretory phospholipase A2 (sPLA2). Tris(2,4-di-tert-butylphenyl)phosphate has anti-inflammatory activity. |
| In vitro | METHODS: KGN, MA-10 and C18-4 cells were treated with Tris(2,4-di-tert-butylphenyl)phosphate (0.1-100 μM) for 48 h. Cell counts were assayed by Hoechst 33342 stained. RESULTS: Tris(2,4-di-tert-butylphenyl)phosphate was not cytotoxic to any of the 3 cell lines. [1] |
| In vivo | METHODS: To assay acute anti-inflammatory activity in vivo, Tris(2,4-di-tert-butylphenyl)phosphate (50-70 mg/kg, 0.1% sodium carboxymethyl cellulose in 1M phosphate buffer pH 7.2) was The carrageenan-induced foot-plantar edema model in rats was administered. RESULTS: Tris(2,4-di-tert-butylphenyl) phosphate at doses of 50 mg/kg and 70 mg/kg exhibited significant anti-inflammatory activity in the carrageenan-induced foot-plantar edema model. tris(2,4-di-tert-butylphenyl) phosphate significantly reduced the volume of raw paw edema. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL (insoluble）, Sonication is recommended. Ethanol : 100 mg/mL (150.85 mM), Sonication is recommended. |
| Keywords | inhibit | Phospholipase | Tris(2,4 di tert butylphenyl)phosphate | Inhibitor | secretory | molecular | anti-inflammatory | sPLA2 | Tris(2,4ditertbutylphenyl)phosphate | docking | Tris(2,4-di-tert-butylphenyl)phosphate |
| Inhibitors Related | Neomycin sulfate | Indomethacin | Lansoprazole |
| Related Compound Libraries | Bioactive Compound Library | Anti-Obesity Compound Library | Natural Product Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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