Trifluoperazine dihydrochloride NEW
| Price | $50 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-09 |
Product Details
| Product Name: Trifluoperazine dihydrochloride | CAS No.: 440-17-5 |
| Purity: 99.96% | Supply Ability: 10g |
| Release date: 2024/11/09 |
Product Introduction
Bioactivity
| 名稱 | Trifluoperazine dihydrochloride |
| 描述 | Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. |
| 體外活性 | Trifluoperazine binds to α1A- and α1B-adrenoceptor with Ki value of 27.6 nM and 19.2 nM, respectively, with α1B/α1A ratio of 0.7. [2] Trifluoperazine inhibits Mycobacterium tuberculosis (Mtb) with MICs of 7.6 μg/mL. [3] Trifluoperazine (< 14.78 mM) suppresses the activities of the mouse splenic NK cell cytotoxicity and the effector-target cell conjugation in a dose dependent manner. Trifluoperazine suppresses interferon-alpha or interleukin-2 induced augmentation of the cytolytic activity of NK cells. [4] Trifluoperazine inhibits the gene expression of voltage-dependent potassium channel Kv2.1 from human brain (hKv2.1). [5] |
| 體內(nèi)活性 | Trifluoperazine dose dependently decreases avoidance responses and increases response failures in rats where behavior is maintained under a discrete-trial avoidance. [6] |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 88 mg/mL (183.2 mM) DMSO : 82 mg/mL (170.7 mM) Ethanol : 89 mg/mL (185.3 mM) |
| 關鍵字 | Trifluoperazine dihydrochloride | Trifluoperazine Dihydrochloride | Trifluoperazine | SKF-5019 | SKF 5019 | schizophrenia | P-gp | Pgp | P-glycoprotein | NUPR1 | Multidrug resistance protein 1 | morphogenesis | MDR1 | Inhibitor | inhibit | Influenza Virus | Dopamine Receptor | Cluster of differentiation 243 | CD243 | CaMK | Calmodulin-dependent protein kinases | Calmodulin-dependent kinases | Beta Receptor | Autophagy | antipsychotic | anticancer | Adrenergic Receptor | ABCB1 |
| 相關產(chǎn)品 | Stavudine | Aceglutamide | Acetylcysteine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Valproic Acid | Curcumin | Paeonol | Naringin | Gefitinib |
| 相關庫 | 神經(jīng)退行性疾病化合物庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | FDA 上市藥物庫 | FDA 上市激酶抑制劑庫 | 抗癌上市藥物庫 | 已知活性化合物庫 | GPCR靶點分子庫 | 抗癌藥物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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