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Postion:Product Catalog >API>Hormones and the Endocrine System>Adrenal corticosteroids>Triamcinolone
Triamcinolone
  • Triamcinolone

Triamcinolone NEW

Price $45
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-05

Product Details

Product Name: Triamcinolone CAS No.: 124-94-7
Purity: 99.54% Supply Ability: 10g
Release date: 2024/11/05

Product Introduction

Bioactivity

名稱Triamcinolone
描述Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to translocation of the ligand-receptor complex to the nucleus and induces expression of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both mediators of inflammation. In addition, pro-inflammatory cytokine production, including interleukin (IL)-1and IL-6, and the activation of cytotoxic T-lymphocytes is also inhibited. T-cells are prevented from making IL-2 and proliferating. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis through increasing Ikappa-B expression and curtailing activation of nuclear factor (NF)kappa-B.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度Ethanol : 1 mg/mL (2.53 mM)
DMSO : 55 mg/mL (139.44 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
關鍵字Bacterial | Inhibitor | Triamcinolone | Glucocorticoid Receptor | inhibit
相關產品Ibuprofen | Acetaminophen | Diclofenac Potassium | Paradol | Indomethacin sodium hydrate
相關庫經典已知活性庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | FDA 上市藥物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌藥物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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