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Postion:Product Catalog >TREM2 agonist-2
TREM2 agonist-2
  • TREM2 agonist-2

TREM2 agonist-2 NEW

Price $283 $698 $1160
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: TREM2 agonist-2 CAS No.: 2738485-98-6
Purity: 98.72% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameTREM2 agonist-2
DescriptionTREM2 agonist-2 (I-192) is an orally active and potent agonist of myeloid triggered receptor 2 (TREM2) for neurodegenerative disease research.
In vitroTreatment with TREM2 agonist-2 (0-100μM; 16 hours) activated hTREM2 in HEK293 cells, with an EC50 value less than 0.05μM for cell viability assay[1].
In vivoThe results indicate that TREM2 agonist-2 (50 mg/kg; twice daily; oral gavage for one day) can bind to the TREM2 target, which can interact with microglial cells[1].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45.19 mg/mL (100 mM), Sonication is recommended.
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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