Tivozanib hydrochloride hydrate NEW
Price | $53 | $74 | $118 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-06 |
Product Details
Product Name: Tivozanib hydrochloride hydrate | CAS No.: 682745-41-1 |
Purity: 98.66% | Supply Ability: 10g |
Release date: 2024/11/06 |
Product Introduction
Bioactivity
名稱 | Tivozanib hydrochloride hydrate |
描述 | Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is an orally active, selective, and potent vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, and VEGFR-3. |
體外活性 | Tivozanib hydrochloride hydrate (0-100 nM; 24 hours) inhibited the proliferation of HUVEC cells[1]. |
體內(nèi)活性 | In the Calu-6 tumor-bearing athymic mice model, Tivozanib hydrochloride hydrate (0.04-1 mg/kg/day; orally, for 14-21 days) inhibits tumor growth, angiogenesis, and vascular permeability[1]. |
存儲條件 | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 100 mg/mL (196.33 mM), Sonication is recommended. |
相關(guān)產(chǎn)品 | Ribociclib | Nintedanib | Regorafenib monohydrate | Sorafenib | Regorafenib | Sanguinarine chloride | Sorafenib tosylate | Lenvatinib mesylate | Pazopanib | Axitinib |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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