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Postion:Product Catalog >Tipranavir
Tipranavir
  • Tipranavir

Tipranavir NEW

Price $125 $397 $597
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-17

Product Details

Product Name: Tipranavir CAS No.: 174484-41-4
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/17

Product Introduction

Bioactivity

名稱Tipranavir
描述Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.
體外活性Tipranavir (PNU-140690) inhibits HIV-1 protease activity, blocks protease subunit dimerization, and exhibits potent efficacy against a broad range of wild-type and multi-PI-resistant HIV-1 variants.[1]
體內(nèi)活性Tipranavir (5 mg/kg ; mouse model): CLtot was 0.17 ± 0.10 L/h/kg, Vss was 0.51 ± 0.14 L/kg, and t1/2 was 5.4 ±0. 3h.[4] Tipranavir (10 mg/kg ; oral ; rats): got the result of F was 30% compared to 5 mg/kg tipranavir dosing.[4]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度Ethanol : 45.0 mg/mL (74.7 mM)
DMSO : 180.0 mg/mL (298.7 mM ), Sonication is recommended.
關(guān)鍵字Tipranavir | PNU 140690 | PNU140690
相關(guān)產(chǎn)品Stavudine | Emtricitabine | Hydroxychloroquine | Lamivudine
相關(guān)庫經(jīng)典已知活性庫 | 上市藥物庫 | EMA 上市藥物庫 | 抗病毒庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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