Product Details
| Product Name:
Thioflosulide |
CAS No.:
158205-05-1 |
| Purity:
100% |
Supply Ability:
10g |
| Release date:
2024/11/20 |
Product Introduction
Bioactivity
| Name | Thioflosulide |
| Description | Thioflosulide (L-745337) is a selective and potent COX2 inhibitor with an IC50 of 2.3 nM, exhibiting anti-inflammatory activity for the study of gastric ulcers. |
| In vivo | In a rat model of postoperative pain, Thioflosulide (L-745337) coadministered intrathecally (40-80 μg) with intrathecal morphine (0.5 nmol) increases withdrawal thresholds dose-dependently. Adding 80 μg of Thioflosulide to 1 nmol of morphine produces a greater antiallodynic effect than morphine at twice the dose. When combined with intrathecal morphine, subcutaneous administration of Thioflosulide (0-30 mg/kg) results in the same antiallodynic response as morphine alone. Thioflosulide also exhibits anti-inflammatory activity, with an effective dose of 0.4 mg/kg and a maximal anti-inflammation dose of 5 mg/kg in arthritic rats. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Thioflosulide | L 745337 | L745337 |
| Inhibitors Related | Ibuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | trans-Cinnamaldehyde | 5-Aminosalicylic Acid | Paradol | Indomethacin sodium hydrate | Trometamol | Glafenine | Revaprazan hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
-
CAS:95656-55-6
$1520.00 / 25mg
-
-
CAS:13093-88-4
$1520.00 / 25mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States