Theaflavin 3,3'-digallate NEW
| Price | $84 | $182 | $297 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: Theaflavin 3,3'-digallate | CAS No.: 30462-35-2 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | Theaflavin 3,3'-digallate |
| 描述 | Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF. |
| 體外活性 | 8-Gingerol has antioxidant activity, inhibiting the formation of superoxide radicals, singlet oxygen, hydrogen peroxide, and hydroxyl radicals in vitro (IC50s = 26.7, 0.83, 0.39, and 25.07 μmol/L, respectively) [1]. |
| 體內(nèi)活性 | In vivo, Theaflavin 3,3'-digallatereduces serum levels of TNF-α, IL-1β, and IL-6 and decreases pulmonary edema, pulmonary congestion, and thickening of the alveolar wall in a mouse model of LPS-induced acute lung injury. It also inhibits osteoclast formation, polarization, and osteoclastic bone resorption in vitro and reduces titanium particle-induced bone erosion and the number of mature osteoclasts in mice in a dose-dependent manner [3]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 10 mg/mL (11.51 mM) Ethanol : 10 mg/mL |
| 關(guān)鍵字 | TF 3 | 0 | TF3 | Theaflavin 3,3'-digallate | ZIKV | Theaflavin 3,3' digallate | ZP10 | HIV | Human immunodeficiency virus | replication | ERK1/2 | p53 | p21 | Akt | U87 | ZP 10 | MAPK | Virus Protease | translation | gp41 | Inhibitor | NF-κB | Theaflavin 3,3'digallate | NS3 | Herpes simplex virus | NS2B-3 | inhibit | HSV | ZP-10 | TF-3 |
| 相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Emtricitabine | Phenytoin sodium | Kaempferol | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | L-Lysine | Valproic Acid | Oxyresveratrol | L-Cystine | Decanedioic acid |
| 相關(guān)庫 | 抗癌天然產(chǎn)物庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | 抗病毒庫 | 高通量篩選天然產(chǎn)物庫 | 抗感染天然產(chǎn)物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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