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Postion:Product Catalog >TH287
TH287
  • TH287

TH287 NEW

Price $31 $41 $66
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: TH287 CAS No.: 1609960-30-6
Purity: 99% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTH287
DescriptionTH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.
In vitroTH287 selectively and effectively kill U2OS and other cancer cell lines with less toxic to several primary or immortalized cells, and induces oxidative DNA damage. [1]
In vivoIn C57Bl/6 mice, TH287 (5 mk/kg, i.p.) causes a peak time and maximum concentration of 0.5 h and 0.82 μM. [2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 10 mg/mL (37.15 mM), Heating is recommended.
DMSO : 49 mg/mL (160.3 mM)
KeywordsTH 287 Hydrochloride | TH-287 | inhibit | TH 287 | TH287 | DNA/RNA Synthesis | TH287 Hydrochloride | TH-287 Hydrochloride | Inhibitor
Inhibitors RelatedRifampicin | 5-Fluorouracil | Ribavirin | Guanidine hydrochloride | 2,4-D | Resveratrol | Trimethoprim | Azelaic acid | Acyclovir | Thymidine | Temozolomide | Folic acid
Related Compound LibrariesDNA Damage & Repair Compound Library | Bioactive Compound Library | Toxic Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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