TH287 NEW
Price | $31 | $41 | $66 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: TH287 | CAS No.: 1609960-30-6 |
Purity: 99% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | TH287 |
Description | TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16. |
In vitro | TH287 selectively and effectively kill U2OS and other cancer cell lines with less toxic to several primary or immortalized cells, and induces oxidative DNA damage. [1] |
In vivo | In C57Bl/6 mice, TH287 (5 mk/kg, i.p.) causes a peak time and maximum concentration of 0.5 h and 0.82 μM. [2] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 10 mg/mL (37.15 mM), Heating is recommended. DMSO : 49 mg/mL (160.3 mM) |
Keywords | TH 287 Hydrochloride | TH-287 | inhibit | TH 287 | TH287 | DNA/RNA Synthesis | TH287 Hydrochloride | TH-287 Hydrochloride | Inhibitor |
Inhibitors Related | Rifampicin | 5-Fluorouracil | Ribavirin | Guanidine hydrochloride | 2,4-D | Resveratrol | Trimethoprim | Azelaic acid | Acyclovir | Thymidine | Temozolomide | Folic acid |
Related Compound Libraries | DNA Damage & Repair Compound Library | Bioactive Compound Library | Toxic Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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