Chinese name: Tekotide

English name: Cosyntropin

CAS: 16960-16-0

EINECS number: 241-031-1

Molecular formula: C28H55NO

MDL number: MFCD00167476

Molecular weight: 421.74

Appearance: This product is a synthetic 24 peptide corticotropin analogue. The sequence of amino acids is the same as the 24 amino acids of the amino end of natural corticotropin (human, bovine, pig), and has the same physiological activity as natural ACTHm.

Density: 1.47± 0.1g /cm3(Predicted)

Storage condition: ?20°C

Solubility: slightly soluble in water.

Form: solid

Water solubility: Soluble in water

Sequence: H-ser-tyr-ser-met-glu-his-phit-arg-trp-gly-lys-pro-val-gly-lys-arg-arg-pro-val-lys-val-tyr-pro-OH

Stability: hygroscopicity

InChIKey: ZOEFCCMDUURGSE-SQKVDDBVSA-N

use

For the diagnosis of adrenal cortical insufficiency; It can also be used to treat rheumatism, rheumatoid arthritis, skin diseases and shock.

Adverse reactions and contraindications: itching, redness, urticaria, bronchospasm and other allergic reactions are less than corticotropin. Occasionally fainting, collapse. Long-term or excessive use can lead to edema, hypertension, hypokalemia, pigmentation and infection, etc. People allergic to natural corticotropin should use with caution.