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Postion:Product Catalog >Tepotinib hydrochloride(1 : x)
Tepotinib hydrochloride(1 : x)
  • Tepotinib hydrochloride(1 : x)

Tepotinib hydrochloride(1 : x) NEW

Price $148 $336 $497
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tepotinib hydrochloride(1 : x) CAS No.: 1103508-80-0
Purity: 99.81% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTepotinib hydrochloride(1 : x)
DescriptionTepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14 skipping mutations.
In vitroTepotinib hydrochloride(1 : x) potently inhibits ABCB1 and ABCG2 efflux transporters, which was confirmed by molecular docking. In addition, Tepotinib hydrochloride(1 : x) inhibited several recombinant cytochrome P450 (CYP) isoforms with varying potency. Tepotinib hydrochloride(1 : x) synergistically reversed daunorubicin and mitoxantrone resistance in cells with ABCB1 and ABCG2 overexpression, respectively[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (94.51 mM)
KeywordsTepotinib hydrochloride(1 : x)
Inhibitors RelatedAtazanavir | Glibenclamide | Encequidar mesylate | L-Ascorbic acid 2-phosphate trisodium | Vismodegib | Vigabatrin | Polyoxyethylene stearate | Chlorpropamide | Probucol | Acridone | Cinchonine | Atazanavir sulfate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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