Tenovin-1 NEW
| Price | $50 | $112 | $202 |
| Package | 10mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: Tenovin-1 | CAS No.: 380315-80-0 |
| Purity: 99.44% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | Tenovin-1 |
| 描述 | Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination. |
| 細胞實驗 | Cell viability isdetermined by trypan blue exclusion, Giemsa staining, or MTT assays.(Only for Reference) |
| 體外活性 | Tenovin-1 (10 μM) protected p53 from mdm 2-mediated degradation, but had little effect on p53 protein synthesis. When applied to p53-expressing tumor cells, Tenovin-1 inhibited cell growth and induced apoptosis.Tenovin-1 is a p53 activator and increased the amount of p53 protein within 2 h of treatment.Tenovin-1 did not affect p53 mRNA levels. |
| 體內活性 | Tenovin-1 (10 μM) protected p53 from mdm 2-mediated degradation, but had little effect on p53 protein synthesis. When applied to p53-expressing tumor cells, Tenovin-1 inhibited cell growth and induced apoptosis.Tenovin-1 is a p53 activator and increased the amount of p53 protein within 2 h of treatment.Tenovin-1 did not affect p53 mRNA levels. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 9.2 mg/mL (25 mM) |
| 關鍵字 | Dihydroorotate Dehydrogenase | Autophagy | Sirtuin | inhibit | MDM-2/p53 | DHODH | Tenovin1 | Tenovin-1 | MDM2 | degradation | acetylation | protein-deacetylating | Inhibitor |
| 相關產品 | Stavudine | Xylitol | Myricetin | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib |
| 相關庫 | 組蛋白修飾化合物庫 | 細胞重編程化合物庫 | 經典已知活性庫 | 自噬庫 | 谷氨酰胺代謝化合物庫 | 抑制劑庫 | 干細胞分化化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 轉錄因子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
| $1.00/1g |
VIP1Y
|
Apeloa production Co.,Limited
|
2024-06-05 | |
| $0.00/1BOX |
VIP1Y
|
Shanghai Affida new material science and technology center
|
2024-05-08 | |
| $5.00/5KG |
VIP7Y
|
Career Henan Chemical Co
|
2019-09-03 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY