Product Details
Product Name:
Telisotuzumab |
CAS No.:
1781223-80-0 |
Purity:
98.5% (SEC-HPLC) |
Supply Ability:
10g |
Release date:
2024/11/15 |
Product Introduction
Bioactivity
名稱 | Telisotuzumab |
描述 | Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with high affinity for c-Met.Telisotuzumab has inhibitory effects on c-Met signaling and antitumor activity. |
體外活性 | Telisotuzumab (ABT-700) (10 μg/mL; 24 h) inhibits SNU5 cell proliferation, increases pro-apoptotic Bim, decreases anti-apoptotic Bcl-xL, and induces apoptosis.[1] |
體內(nèi)活性 | Telisotuzumab (ABT-700) (2.5-40 mg/kg; i.p.; twice a week; 90 days) potently antagonizes constitutively activated c-Met and downstream signaling, thereby inhibiting tumor growth in Hs746T cell-derived SCID mice.[1] |
存儲條件 | store at low temperature | store at -20°C | Shipping with blue ice. |
關(guān)鍵字 | Telisotuzumab | ABT700 | ABT 700 |
相關(guān)產(chǎn)品 | Capmatinib 2HCl | (±)-Norcantharidin | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Amuvatinib | Norcantharidin | AMG-458 | Cabozantinib S-malate | Capmatinib xHCl | Bacitracin Zinc | Capmatinib | BMS 777607 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$827.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |