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Postion:Product Catalog >TCH-165
TCH-165
  • TCH-165

TCH-165 NEW

Price $68 $163 $263
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: TCH-165 CAS No.: 1446350-60-2
Purity: 98.75% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTCH-165
DescriptionTCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.
In vitroTCH-165, resulting in an increase in 20S levels.?The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs, including α-synuclein, tau, ornithine decarboxylase, and c-Fos, but not structured proteins.?Clearance of ubiquitinated protein was largely maintained by single capped proteasome complexes (19S-20S), but accumulation occurs when all 19S capped proteasome complexes are depleted[1].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (83.93 mM)
KeywordsProteasome | tau | trypsin-like | 20S | IDPs | chymotrypsin-like | degradation | α-syn | inhibit | TCH 165 | caspase-like | TCH165 | assembly | TCH-165 | Inhibitor
Inhibitors Related(R)-MG-132 | Sitagliptin | Teneligliptin hydrobromide | Sitagliptin phosphate monohydrate | Anagliptin | Racecadotril | Linagliptin | Aprotinin | Vildagliptin | Alloxan monohydrate | 4'-Hydroxychalcone | Bortezomib
Related Compound LibrariesBioactive Compound Library | Ubiquitination Compound Library | HIF-1 Signaling Pathway Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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