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Postion:Product Catalog >Tazemetostat hydrobromide
Tazemetostat hydrobromide
  • Tazemetostat hydrobromide

Tazemetostat hydrobromide NEW

Price $36 $55 $74
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: Tazemetostat hydrobromide CAS No.: 1467052-75-0
Purity: 99.03% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

NameTazemetostat hydrobromide
DescriptionTazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 nM). Tazemetostat hydrobromide also inhibits EZH1 (IC50: 392 nM).
In vitroTazemetostat hydrobromide inhibits Rat EZH2 (IC50: 4 nM). Tazemetostat hydrobromide inhibits EZH2 with IC50s of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat hydrobromide inhibits multi wild-type and mutant lymphoma cell lines proliferation with IC50s of 0.49 nM-7.6 μM [1].
In vivoTazemetostat (250 or 500 mg/kg twice daily for 21-28 days) practically eliminates the fast-growing G401 tumors [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (152.99 mM), Sonication is recommended.
KeywordsTazemetostat | EPZ 6438 Hydrobromide | E 7438 | EPZ-6438 Hydrobromide | E7438 | PRC2 | Inhibitor | E-7438 | epigenetic | Tazemetostat Hydrobromide | EZH2 | EPZ6438 | EPZ6438 Hydrobromide | EPZ-6438 | Histone Methyltransferase | cancer | Tazemetostat hydrobromide | E 7438 Hydrobromide | E-7438 Hydrobromide | E7438 Hydrobromide | EPZ 6438 | inhibit | EZH1
Inhibitors RelatedBIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719
Related Compound Libraries經(jīng)典已知活性庫 | 血液病分子庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗癌上市藥物庫 | FDA 上市藥物庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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