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Postion:Product Catalog >Tallimustine HCl
Tallimustine HCl
  • Tallimustine HCl

Tallimustine HCl NEW

Price $195 $430 $636
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Tallimustine HCl CAS No.: 118438-45-2
Purity: 98.52% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTallimustine HCl
DescriptionTallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
In vitroTallimustine HCl (0.1-10 μM; 4 h) causes harm to isolated SV40 DNA. Additionally, Tallimustine HCl exhibits cytotoxicity in CEM cells after 72 hours, displaying an IC50 of 3.5 nM.[1] Tallimustine HCl (25 and 100 nM, 6 days) induces erythroid differentiation of K562 cells.[2] Tallimustine HCl (100 nM, 6 days) increases accumulation of γ-globin mRNA in K562 cells.[2] Tallimustine HCl (0.5 μg/mL, 1 h) arrests SW626 cells in G2/M phase.[3]
In vivoTallimustine HCl (3 mg/kg; i.p.; ) prolonged survival and shows antileukemic activity in L1210 tumor-bearing mice and.[4]
StorageShipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (61.3 mM)
KeywordsTallimustine HCl
Inhibitors RelatedNorharmane | Cyclophosphamide hydrate | Quinacrine dihydrochloride | L82 | Proflavine Hemisulfate | Hydroxychloroquine sulfate | Methoxsalen | Cyclophosphamide | BTB09089 | Crystal Violet
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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