tafamidis meglumine NEW
Price | $35 | $60 | $123 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: tafamidis meglumine | CAS No.: 951395-08-7 |
Purity: 99.98% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | tafamidis meglumine |
描述 | Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. |
體外活性 | Tafamidis selectively binds with negative cooperativity (K(d)s ~2 nM and ~200 nM) to the two thyroxine-binding sites of the TTR tetramer, kinetically stabilizing TTR. It also stabilizes patient-derived amyloidogenic TTR variants, including kinetically and thermodynamically less stable mutants[1]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 5.03 mg/mL (10 mM), Sonication is recommended. |
關(guān)鍵字 | tafamidis meglumine | Inhibitor | Tafamidis | inhibit |
相關(guān)庫 | 經(jīng)典已知活性庫 | 上市藥物庫 | 藥物功能重定位化合物庫 | FDA 上市藥物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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