Product Details
Product Name:
STX-478 |
CAS No.:
2883540-92-7 |
Purity:
99.59% |
Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
名稱 | STX-478 |
描述 | STX-478 is an orally active and selective PI3Kα inhibitor that penetrates the blood-brain barrier and has anticancer activity to inhibit tumor growth.STX-478 is indicated for the study of breast cancer and other cancers. |
體外活性 | STX-478 ( 0-10,000 nM ; 1 h ) targeted the MCF10A cells ( with the H1047R kinase domain mutation )[1]. |
體內(nèi)活性 | In Female BALB/c nude mice (CAL-33 xenograft model), STX-478 (30, 100 mg/kg; oral administration) showed a dose-dependent reduction in tumor volume[1]. |
存儲條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 100 mg/mL (249.20 mM), Sonication is recommended.
|
相關(guān)產(chǎn)品 | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Quercetin Dihydrate | Apilimod | LY294002 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$44.50/1g |
|
NanJing Spring & Autumn Biological Engineering CO., LTD.
|
2019-06-25 |