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Postion:Product Catalog >Surfactant>Non-ionic surfactants>Polyol ester type>Span 60
Span 60
  • Span 60
  • Span 60

Span 60 NEW

Price $6 $5 $1
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: Span 60 CAS No.: 1338-41-6
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Name: Sun

1. Product information

Names

NameSpan 60
SynonymMore Synonyms

 Span 60 Biological Activity

DescriptionSorbitan monooctadecanoate is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can be used as an excipient, such as emulsifiers, nonionic surfactants, solubilizers, wetting and dispersing/suspending agents. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog
Research Areas >> Others
Signaling Pathways >> Others >> Others
References

[1]. Murdan S, et al. Novel sorbitan monostearate organogels[J]. Journal of pharmaceutical sciences, 1999, 88(6): 608-614.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

 Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point579.0±45.0 °C at 760 mmHg
Melting Point54-57 °C(lit.)
Molecular FormulaC24H46O6
Molecular Weight430.618
Flash Point185.3±22.2 °C
Exact Mass430.329437
PSA96.22000
LogP7.13
Vapour Pressure0.0±3.6 mmHg at 25°C
Index of Refraction1.497
StabilityStable. Combustible. Incompatible with strong oxidizing agents.

 MSDS

Span 60 MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • WG2933500

  • CHEMICAL NAME :

  • Sorbitan, monostearate

  • CAS REGISTRY NUMBER :

  • 1338-41-6

  • LAST UPDATED :

  • 199710

  • DATA ITEMS CITED :

  • 11

  • MOLECULAR FORMULA :

  • C24-H46-O6

  • MOLECULAR WEIGHT :

  • 430.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • Standard Draize test

  • ROUTE OF EXPOSURE :

  • Administration onto the skin

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • REFERENCE :

  • JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),65,1985 ** ACUTE TOXICITY DATA **

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 31 gm/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • REFERENCE :

  • FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 21,348,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 2730 gm/kg/2Y-C

  • TOXIC EFFECTS :

  • Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - death

  • REFERENCE :

  • TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,315,1959 ** REPRODUCTIVE DATA **

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 635 gm/kg

  • SEX/DURATION :

  • multigenerations

  • TOXIC EFFECTS :

  • Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

  • REFERENCE :

  • JONUAI Journal of Nutrition. (Subscription Dept., 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1928- Volume(issue)/page/year: 60,489,1956

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 1270 gm/kg

  • SEX/DURATION :

  • female 84 day(s) pre-mating - 21 day(s) post-birth

  • TOXIC EFFECTS :

  • Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)

  • REFERENCE :

  • JONUAI Journal of Nutrition. (Subscription Dept., 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1928- Volume(issue)/page/year: 60,489,1956 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),65,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81999 No. of Facilities: 693 (estimated) No. of Industries: 15 No. of Occupations: 25 No. of Employees: 14579 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81999 No. of Facilities: 6199 (estimated) No. of Industries: 63 No. of Occupations: 72 No. of Employees: 189741 (estimated) No. of Female Employees: 71370 (estimated)

 Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
WGK Germany1
RTECSWG2933500
HS Code34021300

 Customs

HS Code2932190090
Summary2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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 Synonyms

EINECS 215-664-9
Drewsorb 60
1,4-anhydro-6-O-octadecanoyl-D-glucitol
D-Glucitol, 1,4-anhydro-5-O-(1-oxooctadecyl)-
1,4-Anhydro-D-glucitol 6-octadecanoate
SPAN(R) 60
Arlacel 60
SPAN(TM) 60
Barchlor 16S
Durtan 60
Glycomul S
1,4-Anhydro-5-O-stearoyl-D-glucitol
D-Glucitol, 1,4-anhydro-, 6-octadecanoate
1,4-Anhydro-D-glucitol, 6-octadecanoate
SPAN NO 60
Span(rg 60
Lonzest(R) SMS
Emsorb 2505
UNII:NVZ4I0H58X
1,4-Anhydro-6-O-stearoyl-D-glucitol
(Sorbitan Monostearate)
Sorbitan stearate Sorbitane monostearate
D-Glucitol, 1,4-anhydro-6-O-(1-oxooctadecyl)-
FEMA 3028
Sorbitan Monostearate
MFCD00005366




2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137





Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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