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Postion:Product Catalog >Chemical Reagents>Organic reagents>Sulfonates / Sulfinates salts>Sodium gualenate
Sodium gualenate
  • Sodium gualenate

Sodium gualenate NEW

Price $34 $48
Package 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: Sodium gualenate CAS No.: 6223-35-4
Purity: 98.35% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱Sodium gualenate
描述Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.
動物實驗The anti-gastric ulcer activity of compounds was tested through an ethanol-induced gastric ulcer mouse model method.?Kunming mice, consisting of both males and females, each weighing about 25 g, were divided into groups of 8 at random.?The tested compounds, Omeprazole and guaiazulene derivatives which were made into suspensions using 5% CMC-Na were administered orally (0.4 mL/20 g) to the dose group, the drug reference group and the GAS-Na group respectively.?While the base control group was treated with only 5% CMC-Na.?Vehicle or test compounds were administered by the oral route once a day for five consecutive days.?After 0.5 h of the last dose, the mice were given orally 0.3 mL of anhydrous ethanol.?Half an hour after anhydrous ethanol administration, the animals were killed.?At last, the stomachs were removed and scored[1].
體內活性Sodium gualenate is frequently used to treat human gastritis, with its primary mechanism of action being the cytoprotection of the stomach's mucosal lining [1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 30 mg/mL (99.88 mM)
關鍵字Sodium gualenate | Inhibitor | inhibit | Guaiazulenesulfonate
相關庫FDA上市及藥典收錄分子庫 | 經典已知活性庫 | 上市藥物庫 | ReFRAME 相關化合物庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 抗纖維化化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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