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Postion:Product Catalog >SNC 80
SNC 80
  • SNC 80

SNC 80 NEW

Price $35 $74 $123
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SNC 80 CAS No.: 156727-74-1
Purity: 98.67% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSNC 80
DescriptionSNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment.
In vitroSNC80 selectively targets and activates the μ-δ heteromer within HEK293 cells, displaying an EC50 value of 52.8 nM. It demonstrates significantly higher activity in cells coexpressing μ- and δ-opioid receptors compared to those solely expressing δ-opioid receptors or those coexpressing δ- and κ-opioid receptors [4].
In vivoSNC80 (10 mg/kg; intraperitoneal injection; once) significantly attenuated allodynia induced by Sumatriptan overuse in C57BL6/J mice [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 1 mg/mL (2.22 mM), Sonication is recommended.
KeywordsSNC-80 | SNC 80 | NIH-10815 | NIH10815
Inhibitors RelatedDocusate sodium | Bevenopran | Mirtazapine | Sinomenine | (-)-Menthol | Matrine | SCH 221510 | Progesterone | Naltrexone hydrochloride | Trimebutine | Mianserin hydrochloride | Amentoflavone
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Antidepressant Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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